Clinical Trials

Colorado Springs Neurological Associates is one of the largest and longest-standing neuroscience medical practices in southern Colorado.  Our aim is to deliver the highest standard of neurological care – the same level of care we would want for ourselves or our loved ones.  The Center has a dedicated clinical research institute with experienced principal investigators and a full-time research staff.  Collectively, our investigators have vast experience conducting phase II through phase IV clinical trials in a broad range of neurologic diseases affecting adults and children.


 

Adult Migraine

  • Phase 4 study evaluating outcomes for migraine patients in real world healthcare systems 
  • Oral ubrogepant in the treatment of migraine when administered during migraine prodromal phase 

Pediatric Migraine

  • Erenumab (Aimovig) for episodic and chronic migraine prophylaxis, 6-18 years of age
  • A multicenter, randomized, double blind, placebo controlled, parallel-group study comparing the efficacy, safety and tolerability of subcutaneous administration of fremanezumab versus placebo for the prophylactic treatment of chronic or episodic migraine in pediatric patients, 6-17 years of age
  • A randomized, double-blind, placebo-controlled study of lasmiditan for acute treatment of migraine 

Multiple Sclerosis

  • Phase 4 observational trial for Multiple Sclerosis patients taking cladribine 
  • Phase 4 observational trial for Multiple Sclerosis patients taking siponimod 
  • Phase 3, randomized, double-blind efficacy and safety study comparing SAR442168 to teriflunomide (Aubagio®) in participants with relapsing forms of multiple sclerosis 
  • Phase 3, randomized, double-blind, efficacy and safety study comparing SAR442168 to placebo in participants with non-relapsing secondary progressive multiple sclerosis 
  • Phase 4 study evaluating the processing speed of MS patients treated with ozanimod  

Neurogenic Orthostatic Hypotension

  • Phase 4 long-term outcome study of droxidopa (Northera) in patients with orthostatic hypotension
  • Phase 3 trial to assess the safety and efficacy of TD-9855 in neurogenic orthostatic hypotension

 Trigeminal Neuralgia

  • Phase 3 study evaluating the efficacy and safety of vixotrigine in subjects with trigeminal neuralgia

 Myasthenia Gravis

  • Phase 3 trial to assess the safety and efficacy of ravulizumab in patients with Myasthenia Gravis
  • Phase 2a, multi-center, randomized, double-blind, placebo- controlled study with an open-label extension of RVT-1401 in Myasthenia Gravis

 

Please contact research coordinator, Jodi for additional information:

Jodi Ventimiglia 719-389-1126  jventimiglia@csneuro.com

Sarah Roberts 719-389-1129 sroberts@csneuro.com

Research Staff